Today, for reasons unknown to us personally, a serious struggle has developed in the market of auxiliary preparations for the athlete, and Nolvadex and Clomid are arguing among themselves, more precisely the athletes are trying to find out which of these drugs is better.
Most of the athletes choose the first option, neglecting his opponent. Although in the fight against ailments that occur after taking steroids, both the drug Clomid and the drug Nolvadex (acting substances clomiphene and Tamoxifen, respectively) have proved themselves well. The first is believed to be an excellent tool for increasing testosterone levels, the second is excellent against gynecomastia. But this is not all that these pharmacological agents are capable of.
And here it becomes unclear why the athletes choose one (in most cases Nolvadex), fundamentally avoiding the other. After all, as proven, Clomid is no less effective. Or the reason for the poor awareness of athletes about the properties of these drugs, or in simple prejudices. Let’s understand.
Clomid and Nolvadex, its Properties and Differences
As we have already said, it is not entirely clear why such similar drugs as Nolvadex and Clomid are used by athletes in different demand. After all, they are not only structurally similar, but both are classified as antagonists of estrogen receptors. That is, from a scientific point of view, these drugs have the most approximate impact, more or less equal in power and efficiency. In addition, both substances are capable at one time and block the effect of estrogens, and act as an estrogen, if necessary (this bilateral effect occurs in various tissues).
On the course, Clomid and Nolvadex are treated as antiestrogenic drugs, that is, they prevent the negative effect of estrogens on the GHN chain. At the same time, they induce our body to produce gonadotropins. As a result, in our body increases the amount of synthesized LH, which in turn leads to an increase in the production of natural testosterone.
Both agents, Clomid and Nolvadex, can boast of this effect, but athletes continue to bend their line, choosing only one particular drug for recovery after the end of taking steroids is tamoxifen.
Of course, these means also have distinctive features. However, they do not vary as much as athletes believe. In order to dot the “I”, we will give the results of some studies, perhaps this will allow justice to triumph.
In the distant and forgotten 70s of the twentieth century in Belgium at the University of Ghent, studies were carried out to study the effects and effects of Nolvadex and Clomid (the drugs were taken separately). During the trials, the influence of both agents on the endocrine system of fully healthy and sexually challenged men was considered. For obvious reasons, we will only refer to the results achieved in testing completely healthy men.
So, in the study were established very, very interesting facts. Tamoxifen at a dosage of 20 mg per day increased the amount of testosterone to 142%, clomiphene to achieve this was used at a dose of 150 mg. In other words, the difference between Clomid and Nolvadex is that 50 mg of the first drug equals 20 mg of the second. Compare their prices, and you will understand what is the main difference between these pharmacological agents.
Nolvadex and Clomid during the Course
But this is not all that scientists have learned. During the experiments aimed at stimulating the synthesis of gonadoliberin, it was found that the drugs mentioned above have completely different effects. So can athletes not be mistaken, believing that Nolvadex is a more powerful drug, and in general that it should be taken for other purposes than Clomiphene? Let’s find out.
In the tests, 100 g of gonadoliberin was administered to volunteers and the amount of LH synthesized was measured. Thus, scientists tried to find out how much the sensitivity of the pituitary gland to this substance, if you enter Nolvadex or a clomiphene similar to it. This was done for one simple reason: as is known, the more sensitive the pituitary gland, the more LH synthesized, and, consequently, the higher the level of secreted testosterone.
This means that the more effective the drug contributes to the action of gonadoliberin, the more it affects the restoration of the level of the male hormone.
The results of the test are as follows: the use of Nolvadex within 10 days increased the sensitivity of the pituitary gland to gonadoliberin several times in comparison with the usual parameters. Clomiphene, in turn, had the opposite effect. That is, the sensitivity of the pituitary gland at the time of its reception has decreased on the contrary.
The dosage of Nolvadex and the rival drug was taken to be comparable in capacity (20 and 50 mg). The result of all of the above is simple: Tamoxifen copes better with increasing the sensitivity of the pituitary gland, and therefore, more affects the secretion of LH and testosterone in the male body, rather than its competitor.
Clomid: Test Results
These differences in the effectiveness of substances primarily due to the difference in their estrogenic structure. Although they are similar, but still in different parts of our body Clomid acts differently than tamoxifen does, and vice versa.
Referring to the facts, it can be argued that tamoxifen today is a stronger anti-estrogen in parts of our body such as the pituitary and hypothalamus. While the drug Clomid there, in the pituitary and hypothalamus, acts weaker or has the opposite effect.
This fact can be confirmed by a thousand. We, for this purpose, will resort to the results of yet another study, conducted in 1981 by scientists from the American Journal of Physiology. Tests were then placed on animals. In this paper, we examined how tamoxifen and clomiphene affect the production of LH in the pituitary gland of rats.
The results coincided with later studies in humans: Clomid administration had less effect, and tamoxifen showed excellent results, in addition, its effect was milder.
Summing up, let’s say: Tamoxifen is a more pure anti-estrogen. It is considered more effective when it is necessary to restore the work of the GGN (hypothalamus-pituitary-testicles). It is for this reason that most of the athletes resort to its use. The use of Clomid on GSN does not affect so much, but this does not mean that the drug is much worse, because it can act where it is not capable of tamoxifen. And that means he will find his place in bodybuilding. So do not put a cross on the use of neither one nor the other drug. Both of them will be useful to you.
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